Isaac Manyonda

Isaac Manyonda - BSc MBBS PhD MRCOG

Consultant Gynaecologist Obstetrician - BSc MBBS PhD MRCOG


Isaac Manyonda is a Senior Obstetrician and Gynaecologist at St George’s Hospital, South London, and Reader in Obstetrics and Gynaecology at St George’s University of London. He was appointed to the Consultant staff in 1994 and over the years has brought numerous innovations to the service including setting up a pioneering dedicated Myoma (Fibroid) Clinic, a busy recurrent miscarriage service, and undertaking ground breaking research, some of which has been published in prestigious and high impact factor journals including the New England Journal of Medicine, Nature, Lancet and the BMJ.

He is a keen teacher for both under- and postgraduates, and runs highly popular revision courses for the Part II MRCOG examinations in London as well as in Bengaluru, India. His current clinical interests include high risk obstetrics and he runs combined clinics for women with diabetes in pregnancy and women with connective tissue disorders. He is an accomplished minimally invasive (key-hole) surgeon.

He runs a general gynaecology clinic as well as a dedicated Recurrent Miscarriage Clinic once a week. His major gynaecological interest is in fibroid disease, and he runs two clinics per week dedicated to women with fibroids. He has develop novel techniques to minimize blood loss and adhesion formation in fibroid surgery, including the use of sub-serosal surgicell to minimize oozing from uterine suture lines, and the use of pre-myomectomy uterine artery embolisation to minimize surgical blood loss and enable myomectomy for massive uterine fibroids where most gynaecological surgeons might offer hysterectomy – thus preservation of fertility is a major priority in his practice.

He collaborates closely with interventional radiologists to provide a wide range of treatment options for women with fibroids, and has researched and written extensively on the condition, including editing a volume of 12 extensive reviews on Uterine Fibroids.

Isaac Manyonda was educated at Waterford/Kamhlaba School (Swaziland) and Westminster School, London, and undertook his undergraduate training in Medicine at the same St George’s Hospital where he is now a consultant. His training in obstetrics and gynaecology was undertaken at diverse teaching and district general hospitals including the Leicester Royal Infirmary and its sister hospitals, and hospitals in the south west of England. He horned his skills in minimal access surgery during his senior registrar tenure at St Peter’s Hospital, Chertsey, which is recognized as one of the pioneering and leading centers in the techniques.

In 1988 he was awarded the highly prestigious MRC Training Fellowship and spent the following three years in the Immunology Laboratory at St George’s Hospital Medical where he undertook laboratory research on the materno-fetal immunological relationship, and was subsequently awarded a PhD for a thesis on the subject. He has since researched and written extensively on immunological aspects of human reproduction, and has written a book “The Immunology of Human Reproduction”.

Despite a punishing clinical schedule he remains highly research active, with interests that include recurrent miscarriage, pre-eclampsia, fibroid disease, and surgical techniques in gynaecology. To support his research over the years he has managed to secure substantial research funding from charities that include the MRC, Wellcome Trust, Sir Jules Thorne, Birthright, and NHS R&D to name a few. He has supervised numerous research fellows who have gone on to be awarded PhD’s and MD’s, and now undertake extensive research in their own right.

National and international activities: He is a recognized teacher and Examiner of the University of London, and a visiting examiner for the undergraduate obstetrics & gynaecology curriculum at the University of Zimbabwe, and the postgraduate curriculum at the University of Malaysia. He has been a member of the FIGO Advisory panel since 2001, and was MCQs Editor, Best Practice in Obstetrics & Gynaecology, from 2001 to 2005. He served on the Part MRCOG MCQs Committee for three years, and is currently the RCOG representative on the DOH’s Diabetes in Pregnancy Steering Committee. He is on the editorial board of numerous journals in Obstetrics & Gynaecology.

He has recently established a strong collaboration with colleagues in India, and is Scientific Advisor to ARTIST (Asian Research and Training Institute for Skill Transfer). Collaborative research topics include anaemia in pregnancy and the role of intravenous iron therapy, and diabetes in pregnancy.

Isaac Manyonda offers private consultations and out- and in-patient treatment at the Parkside Hospital, Wimbledon, and St Anthony’s Hospital, Cheam. He also delivers women at the Portland Hospital, West London. Appointments can be made via his private secretary or directly via the hospitals appointments desks (details on the website).


  • Women's Health – Women’s Health Clinic Website, Dedicated to Gynecological Disorders. Information on a wide range of women’s health disorders & symptoms women may experience.